Injectable Dermal Fillers Microspheres

EPRUI supplies high quality microspheres which are widely used raw material as injectable dermal fillers.

  • Medical Grade PMMA Microspheres

  • Calcium Hydroxyapatite Microspheres
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  • 25-45um HAP microspheres for injectable filler
  • 40um PMMA microspheres for injectable dermal filler

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Complete Buying Guide of Dermal Filler Used Microspheres

Dermal fillers, also known as injectable implants, soft tissue fillers, or wrinkle fillers are gel-like substances that are injected beneath the skin to restore lost volume, smooth lines, and soften creases, or enhance facial contours.

Since the filler is injected into human body, it needs to be approved by the FDA for medical device implants use in helping to create a smoother and/or fuller appearance in the face, including nasolabial folds (the lines extending from the sides of the nose to the edges of the mouth), cheeks, chin, lips, and back of the hands.

1. Why choose dermal fillers?

Compared with surgical plastic surgery, micro plastic surgery by injecting dermal fillers beneath the skin is much safer and less painful. There is no bleeding and no wound left. Basically there is no need of recovery period, which make the beauty lovers become beautiful and young in a short time.

2. What are commonly used dermal filler made with?

There are a variety of FDA approved filler products that cosmetic surgeons use. In general, fillers are categorized by degradation properties: Biodegradable and Non-biodegradable.

Injectable Dermal FillerDegradation propertiesDurabilityFDA Approved Brand
Hyaluronic Acid (HA)Biocompatible, Biodegradable6-12 monthsJuvéderm products: Juvéderm XC, VOLUMA, VOLBELLA, VOLLURE
Restylane products: Restylane, Restylane Silk, Restylane Lyft, Restylane Refyne, and Restylane Defyne; Belotero Balance
Calcium Hydroxyapatite Microspheres (HAP)Biocompatible,
Poly-L-lactic AcidBiocompatible, Biodegradable18-24monthsSculptra 
Botulinum ToxinBiocompatible, Biodegradable6 monthsBOTOX
Polymethylmethacrylate /PMMA MicrospheresBiocompatible,
5 yearsBellafill (formerly known as Artefill)
Note: always make sure that you are receiving FDA approved, brand name fillers, which are only available through a licensed physician, such as a board certified cosmetic surgeon.

3. What types of dermal filler used microspheres can EPRUI supply?

  • 38-42um PMMA microspheres
  • 25-45um HAP microspheres
  • Porous beta TCP microspheres
  • 40-63um PLLA microspheres

4. Which injectable wrinkle filler do I need?

  • Smooth brow furrows, crow’s feet, frown line — BOTOX type injectables(neurotoxins) are best for these expression lines
  • Smooth under the eyes/tears troughs — Hyaluronic Acid fillers, autologus fat injection
  • Lift& enhance cheeks — Hyaluronic Acid fillers, autologus fat injection
  • Soften nasolabial folds (>12 months)  —- Hyaluronic Acid fillers, Radiesse(Calcium Hydroxyapatite microspheres)
  • Soften nasolabial folds (>12 months)  —- Sculptra (Poly-L-lactic Acid microspheres),Bellafill(PMMA microspheres)
  • Smooth vertical lip lines — Hyaluronic Acid fillers
  • Smooth marionette lines — Hyaluronic Acid fillers, autologus fat injection
  • Plump the lips — Hyaluronic Acid fillers, autologus fat injection
  • Smooth chin wrinkles — Hyaluronic Acid fillers, Radiesse(Calcium Hydroxyapatite microspheres)
  • Fill acne scars — Bellafill(PMMA microspheres), Radiesse(Calcium Hydroxyapatite microspheres)
  • Rejuvenate hands — Radiesse(Calcium Hydroxyapatite microspheres), autologus fat injection

5. Who can use our microspheres to make dermal fillers?

Our PMMA or HAP microspheres are raw materials for making dermal fillers.

We do not suggest individuals buy our microspheres to make their own fillers. Please go to a licensed physician, such as a board-certified cosmetic surgeon. Make sure the fillers are FDA, CE or ANVISA approved.

6. What are the risks of using injectable dermal fillers?

Common risks include: Bruising, Redness, Swelling, Pain, Tenderness, Itching, Rash, difficulty in performing activities (only observed when injected into the back of the hand).

Less common risks include: Raised bumps in or under the skin (nodules or granulomas) that may need to be treated with injections, oral antibiotics, or surgically removed, infection, open or draining wounds, a sore at the injection site, allergic reaction, necrosis (tissue death)

7. Who are forbidden to take dermal filler injection?

  • Pregnant, while breast feeding or people under 22 years of age.
  • Your skin is inflamed or infected. If you have an active inflammatory condition (cysts, pimples, rashes, or hives) or infection, dermal filler injection should be delayed until this inflammatory condition has been managed.
  • You have a bleeding disorder.
  • You have severe allergies or have a history of anaphylaxis (acute allergic reaction).
  • You are allergic to collagen or eggs (some dermal fillers contain collagen or egg-derived products).
  • You are allergic to animal products (some dermal fillers contain materials from animals).
  • You are allergic to local anesthetic such as lidocaine (some dermal fillers contain lidocaine).
  • You are allergic to bacteria (some dermal fillers contain hyaluronic acid material derived from bacterial fermentation).
  • You have joint, tendon, or blood vessel disease affecting the hand, when considering hand augmentation.

8. What are the costs for different dermal fillers?

Generally, the cost from high to low is as below:

Botulinum Toxin > Hyaluronic Acid fillers > Poly-L-lactic Acid filler > Calcium Hydroxyapatite filler > PMMA filler

9. How to order

Please send e-mail to: or call us by 86-21-64192663 for products inquires.

For detailed steps, please visit: How to Buy

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