The structure of magnetic beads functionalized with rich silanol groups is typically core shell type. The core is superparamagnetic Fe3O4 nanoparticles which is coated with silica layer as shell. This type of magnetic microspheres is superficially functionalized with rich silanol groups.
They are specially designed for nucleic acid extraction and isolation. Magnetic beads functionalized with Si-OH groups can quickly isolate nucleic acid under the condition of high salt and low pH in the solution by hydrophobic interaction, hydrogen-bond and electrostatic interaction with proteins and other contents in biological samples.
Our magnetic silica beads for DNA extraction are safe and easy to operate, especially suitable for automated and high-throughput applications.