Functionalized Silica Microspheres

>>>Functionalized Silica Microspheres
Functionalized Silica Microspheres2018-10-17T13:21:05+00:00

Project Description

Our functionalized silica microspheres including carboxyl, amino, epoxy, aldehyde, groups are suitable for the covalent immobilization of polypeptide, protein, antibody, oligonucleotides and other biomolecules.

Microspheres with particle size below 3um are supplied as a 10% solids suspension (100mg/mL) in de-ionized water with surfactant and sodium azide.

Microspheres with particle size larger than 3um are usually supplied in powder form but can also be supplied in dispersion form according to customers’ requirement.

functionalized silica microspheres

Carboxyl Silica Microbeads

Our carboxylate-modified silica microspheres are suitable for the covalent immobilization of proteins, peptides, and nucleic acids. EDAC-mediated coupling is often used for the covalent immobilization of amine-terminated proteins, DNA, or other molecules on carboxyl-functionalized silica microspheres.

Carboxyl Silica MicrobeadsParticle Size(um)MatrixC.VFunctional Groups
2-002-0.10.1SiO2<3.5%-COOH
2-002-0.50.5SiO2<3.5%-COOH
2-002-11SiO2<3.5%-COOH
2-002-33SiO2<3.5%-COOH
2-002-55SiO2<3.5%-COOH
2-002-1010SiO2<3.5%-COOH
2-002-1515SiO2<3.5%-COOH
2-002-2020SiO2<3.5%-COOH
2-002-3030SiO2<3.5%-COOH
2-002-4040SiO2<5%-COOH
2-002-5050SiO2<5%-COOH
2-002-100100SiO2<10%-COOH

Amine Silica Microspheres

Amino methyl functionalized microspheres offer further options for coupling of biomolecules. Glutaraldehyde is commonly used for the immobilization of amine-containing compounds, and specialized linkers are available for targeted coupling of thiol or carbohydrate moieties.

Amine Silica MicrospheresParticle Size(um)MatrixC.VFunctional Groups
2-003-0.10.1SiO2<3.5%-NH2
2-003-0.50.5SiO2<3.5%-NH2
2-003-11SiO2<3.5%-NH2
2-003-33SiO2<3.5%-NH2
2-003-55SiO2<3.5%-NH2
2-003-1010SiO2<3.5%-NH2
2-003-1515SiO2<3.5%-NH2
2-003-2020SiO2<3.5%-NH2
2-003-3030SiO2<3.5%-NH2
2-003-4040SiO2<5%-NH2
2-003-5050SiO2<5%-NH2
2-003-100100SiO2<10%-NH2

We offer customization for epoxy, silanol, aldehyde, methyl functionalization. If have special requirement, please feel free to contact us.

Request A Quote