Project Description

Hydroxyapatite Whisker

Medical grade HAP whiskers are short HA fibers synthesized in simulated body fluid. HAP whiskers are used as reinforcement materials for bioactive composite materials for bone regeneration, dental implants, etc.

  • EPRUI supplies HAP whiskers which meet Chinese standard YY0303-1998 and International Standard ASTM F 1185-2003

  • Our lab meets GMP requirement

  • EPRUI uses the method of simulating body fluid to produce medical use HA whiskers

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Hydroxyapatite Whisker

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HAP Whisker Physical Property

Chemical nameHydroxyapatite Whisker,HAP/HA whiskers
Item No.EPRUI-HAw
AppearanceWhite powder or granules
MorphologyHexagonal
GradeMedical Grade
StandardYY0303-1998 and International Standard ASTM F 1185-2003
Molecular Weight1004
Formula Ca10(PO4)6(OH)2
Cas No.1306-06-5
Density3.16g/cm3
Melting Point1650 ℃
Mohs Hardness Scale5
Ca23.0 ~ 25.5%
P9.0 ~ 11.5%
H2O≤5.0%
Acid insoluble≤0.1%
As≤0.0003%
Heavy metals≤0.001%
Diameter1 ~ 5μm
Length to diameter ratio10~300

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Buying Guide of Medical Grade Hydroxyapatite Whisker

1. Molecular Structure of medical HAP Whiskers

2. What are applications of medical HAP whiskers?

HAP whiskers have high specific strength, high specific modulus, better creep resistance, and high temperature resistant performance. Relying on the energy produced by whisker bridging, crack deflection, and pullout effects, it eliminates stress concentrated at the crack tip.

Whiskers bears stress through load transfer, thereby reducing the stress on the surrounding matrix material and achieving the purpose of enhancing the toughness of the biological material, which can effectively improve the mechanical properties of the material.

Based on the above advantages, HAP whiskers are usually doped into the material to prepare the repair material for the main bone defect.

3. What are the synthesis methods for HAP whiskers?

Solid-phase reaction method, sol-gel method, hydrothermal method and homogeneous precipitation method.

4. What are differences between medical HAP and HAP whiskers?

Hydroxyapatite (Ca10 (PO4) 6 (OH)2), abbreviated as HA or HAP, has similar chemical composition and structure to the bone tissue of living organisms. It has good biocompatibility and biological activity. When implanted into human body, it has no toxic and side effects such as irritation and rejection.

What’s more, HAP material has good bone conductivity and can form a strong chemical bond with the tissue at the interface. Therefore, hydroxyapatite is widely used in the field of biomedical implant materials.

However, HAP is more brittle and lower in strength than human bones. Due to the poor mechanical properties, it greatly limits HAP use in human body load parts. HAP can only be applied to non-load-bearing small implants, such as artificial dental bones, ear bones, fillings Bone defects, etc. Studies have shown that compared to amorphous whiskers, whisker-like HAP has high specific strength, high specific modulus, better creep resistance, and high temperature resistant performance.

Relying on the energy produced by whisker bridging, crack deflection, and pullout effects, it eliminates stress concentrated at the crack tip. Whiskers bears stress through load transfer, thereby reducing the stress on the surrounding matrix material and achieving the purpose of enhancing the toughness of the biological material, which can effectively improve the mechanical properties of the material .

Based on the above advantages, HAP whiskers are usually doped into the material to prepare the repair material for the main bone defect.

5. Why choose HAP whiskers from EPRUI?

  • EPRUI supplies HAP whiskers which meet Chinese pharmaceutical standards YY / T 0683-2008 which is corresponding to International Standard ASTM F 1088-04a
  • The lab to make medical grade HA and TCP biological materials is built according to GMP requirement.
  • EPRUI uses the method of simulating body fluid to produce medical use HA whiskers, which makes the product more biocompatible.
  • EPRUI provides customization service and professional technical support for your research products.

6. How to order

Please send e-mail to: [email protected] or call us by 86-21-64192663 for products inquires.

For detailed steps, please visit: How to Buy

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