In this method, the purification medium is coated on the surface of magnetic beads. Through the adsorption of DNA by the medium, the DNA is attached to the magnetic beads and moved directionally under the action of external magnetic field, so as to achieve the purpose of separating nucleic acid from other substances.
Compared with other purification methods, the magnetic silica bead method has incomparable advantages.
The extraction sensitivity is high (only a small amount of sample is needed);
The purity of purification is high (the nucleic acid can be completely separated from impurities);
The yield of extraction was high (500 μ g DNA per mg magnetic beads);
The separation speed is fast (magnetic separation only takes a few seconds);
Automatic operation (through the machine to complete the operation process automatically, without manpower);
High throughput extraction (hundreds of samples can be extracted simultaneously);
Non toxic, harmless and pollution-free (the reagent does not contain any toxic substances).